STUDY: DEVELOPMENT OUTCOMES IN CHILDREN BORN AFTER CAPA-IVM COMPARED TO CONVENTIONAL IVF

 

KUALA LUMPUR, July 6 (Bernama) -- A new two-year infant follow-up study reported no difference in developmental outcomes in children born after capacitation-in vitro maturation (CAPA-IVM) compared to those born through conventional in vitro fertilisation (IVF) following ovarian stimulation.

According to a statement, the study was designed to detect developmental delay in children in terms of communication, gross motor, fine motor, problem solving and personal-social behaviour.

It included a total of 231 children who were evaluated at six months, 12 months and 24 months after birth.

The study results were presented by Prof Dr Tuong M Ho at the 38th Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) on July 6, 2022 in Milano (Italy) and have been published in Human Reproduction, a leading reproductive medicine journal.

Prof Dr Lan Vuong from MyDuc hospital, HCMC, Vietnam, who led the study, said: “One of the key messages of this study is that there does not appear to be any significant concern about the safety of CAPA-IVM on childhood development.”

The current results complement recent findings that CAPA-IVM does not show any major epigenetic alterations or imprinting defects in in-vitro matured oocytes.

Dr Vuong believes that continuing building evidence on CAPA-IVM is important to physicians considering alternative approaches to current fertility treatment.

CAPA-IVM is a novel approach to in-vitro maturation of oocytes recovered after no or minimal ovarian stimulation, that incorporates a capacitation step in the maturation of oocytes in vitro which enhances oocyte developmental competence.

The worldwide rights to the CAPA-IVM technology are owned by Lavima Fertility Inc.

-- BERNAMA